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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 983872Generated: October 26, 2026

Malononitrile, benzylidene- → 5-Aminomethyl-2-(1H-indol-2-yl)-6-phenyl-pyrimidin-4-ylamine

https://huagongshe.com/reaction/983872

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMalononitrile, benzylidene-HCID 17608—
Reactant1H-Indole-2-carboximidamideHCID 135677716—
Product5-Aminomethyl-2-(1H-indol-2-yl)-6-phenyl-pyrimidin-4-ylamineHCID 10171905—

Reaction Steps

The title compound, MS: m/e=315.8 (M+H+), was prepared from 1H-indole-2-carboxamidine and 2-benzylidene-malononitrile in analogy to the process described in Example 11 as a solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06867205B2
Source datasetuspto-grants-2005_03
ORD IDord-cd638d4062e24c6680ebb0d3cc4cb564
Source noteuspto-grants-2005_03