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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 983875Generated: October 25, 2026

Malononitrile, benzylidene- → 5-Aminomethyl-6-phenyl-2-thiophen-2-yl-pyrimidin-4-ylamine

https://huagongshe.com/reaction/983875

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMalononitrile, benzylidene-HCID 17608—
ReactantThiophene-2-carboximidamideHCID 2781760—
Product5-Aminomethyl-6-phenyl-2-thiophen-2-yl-pyrimidin-4-ylamineHCID 22220606—

Reaction Steps

The title compound, MS: m/e=282.8 (M+H+), was prepared from thiophene-2-carboxamidine and 2-benzylidene-malononitrile in analogy to the process described in Example 11 as a solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06867205B2
Source datasetuspto-grants-2005_03
ORD IDord-5849801c80f64fdaa591bd3f024743f2
Source noteuspto-grants-2005_03