(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)acetamide → 3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(6-chloro-1H-indol-3-yl)pyrrole-2,5-dione

HRID 983954Notes

Reaction equation

HRID 983954 reaction equation
CO[C:3](=[O:16])[C:4]([C:6]1[C:14]2[C:9](=[CH:10][C:11]([Cl:15])=[CH:12][CH:13]=2)[NH:8][CH:7]=1)=O.[C:17]1([CH2:29][C:30]([NH2:32])=[O:31])[C:27]2=[C:28]3[C:23](=[CH:24][CH:25]=[CH:26]2)[CH2:22][CH2:21][CH2:20][N:19]3[CH:18]=1>>[C:17]1([C:29]2[C:30](=[O:31])[NH:32][C:3](=[O:16])[C:4]=2[C:6]2[C:14]3[C:9](=[CH:10][C:11]([Cl:15])=[CH:12][CH:13]=3)[NH:8][CH:7]=2)[C:27]2=[C:28]3[C:23](=[CH:24][CH:25]=[CH:26]2)[CH2:22][CH2:21][CH2:20][N:19]3[CH:18]=1

Participants

3

Reactant 2

HCID 16742967(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)acetamideHCID 69745069methyl 2-(6-chloro-1H-indol-3-yl)-2-oxoacetate

Product 1

HCID 225566793-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(6-chloro-1H-indol-3-yl)pyrrole-2,5-dione

Procedure

Beginning with 6-chloroindole-3-glyoxylic acid methyl ester and 2-(5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-acetamide, the title compound was prepared as a dark red foam essentially as described in Example 1.

Sources & evidence

ORD record
ord-6746e752044c42088c65a11af251c389
Source dataset
uspto-grants-2005_03
Patent number
US06867198B2

Reaction notes

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