(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)acetamide → 3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(7-cyano-1H-indol-3-yl)pyrrole-2,5-dione

HRID 983956Notes

Reaction equation

HRID 983956 reaction equation
CO[C:3](=[O:17])[C:4]([C:6]1[C:14]2[C:9](=[C:10]([C:15]#[N:16])[CH:11]=[CH:12][CH:13]=2)[NH:8][CH:7]=1)=O.[C:18]1([CH2:30][C:31]([NH2:33])=[O:32])[C:28]2=[C:29]3[C:24](=[CH:25][CH:26]=[CH:27]2)[CH2:23][CH2:22][CH2:21][N:20]3[CH:19]=1>>[C:18]1([C:30]2[C:31](=[O:32])[NH:33][C:3](=[O:17])[C:4]=2[C:6]2[C:14]3[C:9](=[C:10]([C:15]#[N:16])[CH:11]=[CH:12][CH:13]=3)[NH:8][CH:7]=2)[C:28]2=[C:29]3[C:24](=[CH:25][CH:26]=[CH:27]2)[CH2:23][CH2:22][CH2:21][N:20]3[CH:19]=1

Participants

3

Reactant 2

HCID 16742967(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)acetamideHCID 697439417-Cyanoindole-3-glyoxylic acid methyl ester

Product 1

HCID 225568273-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(7-cyano-1H-indol-3-yl)pyrrole-2,5-dione

Procedure

Beginning with 7-cyanoindole-3-glyoxylic acid methyl ester and 2-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)acetamide, the title compound was prepared essentially as described in Example 1.

Sources & evidence

ORD record
ord-04b2188822924540a8879572fa608d5d
Source dataset
uspto-grants-2005_03
Patent number
US06867198B2

Reaction notes

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