2-(6,6-dimethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)acetamide → HCID 22556816, compound

HRID 983962Notes

Reaction equation

HRID 983962 reaction equation
C[O:2][C:3](=O)[C:4]([C:6]1[C:14]2[C:9](=[C:10]([CH2:15][CH2:16][CH2:17][O:18][Si:19]([CH:26]([CH3:28])[CH3:27])([CH:23]([CH3:25])[CH3:24])[CH:20]([CH3:22])[CH3:21])[CH:11]=[CH:12][CH:13]=2)[NH:8][CH:7]=1)=O.[CH3:30][C:31]1([CH3:47])[C:40]2[C:35]3=[C:36]([C:41]([CH2:43][C:44]([NH2:46])=[O:45])=[CH:42][N:34]3[CH2:33][CH2:32]1)[CH:37]=[CH:38][CH:39]=2>>[CH:26]([Si:19]([CH:20]([CH3:22])[CH3:21])([CH:23]([CH3:25])[CH3:24])[O:18][CH2:17][CH2:16][CH2:15][C:10]1[CH:11]=[CH:12][CH:13]=[C:14]2[C:9]=1[NH:8][CH:7]=[C:6]2[C:4]1[C:3](=[O:2])[NH:46][C:44](=[O:45])[C:43]=1[C:41]1[C:36]2=[C:35]3[C:40](=[CH:39][CH:38]=[CH:37]2)[C:31]([CH3:47])([CH3:30])[CH2:32][CH2:33][N:34]3[CH:42]=1)([CH3:27])[CH3:28]

Participants

3

Reactant 2

HCID 225567562-(6,6-dimethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)acetamideHCID 69743568HCID 69743568, compound

Product 1

HCID 22556816HCID 22556816, compound

Procedure

Beginning with 7-((triisopropylsilyloxy)propyl)indole-3-glyoxylic acid methyl ester and 2-(6,6-dimethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)acetamide, the title compound was prepared essentially as described in Example 1.

Sources & evidence

ORD record
ord-303b9171aa1340e09bb86c5200ab00fb
Source dataset
uspto-grants-2005_03
Patent number
US06867198B2

Reaction notes

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