(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)acetamide → HCID 22556767, compound

HRID 983963Notes

Reaction equation

HRID 983963 reaction equation
CO[C:3](=[O:29])[C:4]([C:6]1[C:14]2[C:9](=[CH:10][C:11]([CH2:15][CH2:16][CH2:17][O:18][Si:19]([CH:26]([CH3:28])[CH3:27])([CH:23]([CH3:25])[CH3:24])[CH:20]([CH3:22])[CH3:21])=[CH:12][CH:13]=2)[NH:8][CH:7]=1)=O.[C:30]1([CH2:42][C:43]([NH2:45])=[O:44])[C:40]2=[C:41]3[C:36](=[CH:37][CH:38]=[CH:39]2)[CH2:35][CH2:34][CH2:33][N:32]3[CH:31]=1>>[C:30]1([C:42]2[C:43](=[O:44])[NH:45][C:3](=[O:29])[C:4]=2[C:6]2[C:14]3[C:9](=[CH:10][C:11]([CH2:15][CH2:16][CH2:17][O:18][Si:19]([CH:23]([CH3:24])[CH3:25])([CH:20]([CH3:22])[CH3:21])[CH:26]([CH3:27])[CH3:28])=[CH:12][CH:13]=3)[NH:8][CH:7]=2)[C:40]2=[C:41]3[C:36](=[CH:37][CH:38]=[CH:39]2)[CH2:35][CH2:34][CH2:33][N:32]3[CH:31]=1

Participants

3

Reactant 2

HCID 16742967(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)acetamideHCID 69745082HCID 69745082, compound

Product 1

HCID 22556767HCID 22556767, compound

Procedure

Beginning with 6-((triisopropylsilyloxy)propyl)indole-3-glyoxylic acid methyl ester and 2-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-acetamide, the title compound was prepared essentially as described in Example 1.

Sources & evidence

ORD record
ord-27573d492c0542678fc05a5619e22b38
Source dataset
uspto-grants-2005_03
Patent number
US06867198B2

Reaction notes

Loading…