Dichloromethane → N-(7-chloro-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-N'-(4-methoxy-2-methylphenyl)-urea

HRID 98399Notes

Reaction equation

HRID 98399 reaction equation
[Cl:34][CH2:35][Cl:36].[N:22](=[C:23]=[O:24])[c:25]1[c:26]([CH3:33])[cH:27][c:28]([O:31][CH3:32])[cH:29][cH:30]1.[NH2:1][CH:2]1[C:3](=[O:21])[N:4]([CH3:20])[c:5]2[c:6]([cH:15][c:16]([Cl:19])[cH:17][cH:18]2)[C:7]([c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)=[N:8]1>>[NH:1]([CH:2]1[C:3](=[O:21])[N:4]([CH3:20])[c:5]2[c:6]([cH:15][c:16]([Cl:19])[cH:17][cH:18]2)[C:7]([c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)=[N:8]1)[C:23]([NH:22][c:25]1[c:26]([CH3:33])[cH:27][c:28]([O:31][CH3:32])[cH:29][cH:30]1)=[O:24]

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 27349054-Methoxy-2-methylphenyl isocyanateHCID 221352663-amino-7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one

Product 1

HCID 10151750N-(7-chloro-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-N'-(4-methoxy-2-methylphenyl)-urea

Sources & evidence

ORD record
ord-1941b91a58164c6d9006c896a6b621ad
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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