HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(6-bromo-1H-indol-3-yl)acetamide → 3-(6-Bromo-1H-indol-3-yl)-4-(5-hydroxymethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-pyrrolidine-2,5-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(6-bromo-1H-indol-3-yl)acetamide | HCID 23427609 | — |
| Reactant | (5-(hydroxymethyl)-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl]oxo-acetic acid methyl ester | HCID 69742637 | — |
| Product | 3-(6-Bromo-1H-indol-3-yl)-4-(5-hydroxymethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-pyrrolidine-2,5-dione | HCID 22556683 | — |
Reaction Steps
Beginning with (5-(hydroxymethyl)-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl]oxoacetic acid methyl ester and (6-bromo-1H-indol-3-yl)acetamide, the title compound was prepared essentially as described in Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06867198B2 |
| Source dataset | uspto-grants-2005_03 |
| ORD ID | ord-5bc5b8a7776d4791b8ed03b549c586e9 |
| Source note | uspto-grants-2005_03 |