HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-trifluoromethyl-1H-indol-3-yl-acetamide → 3-(5-Hydroxymethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(6-trifluoromethyl-1H-indol-3-yl)-pyrrolidine-2,5-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-trifluoromethyl-1H-indol-3-yl-acetamide | HCID 21950060 | — |
| Reactant | (5-(hydroxymethyl)-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl]oxo-acetic acid methyl ester | HCID 69742637 | — |
| Product | 3-(5-Hydroxymethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(6-trifluoromethyl-1H-indol-3-yl)-pyrrolidine-2,5-dione | HCID 22556736 | — |
Reaction Steps
Beginning with (5-(hydroxymethyl)-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl]oxo-acetic acid methyl ester and (6-(trifluoromethyl)-1H-indol-3-yl)acetamide, the title compound was prepared essentially as described in Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06867198B2 |
| Source dataset | uspto-grants-2005_03 |
| ORD ID | ord-a27baa075f534926894bee36b41186a9 |
| Source note | uspto-grants-2005_03 |