HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(6-Methoxy-1H-indol-3-yl)acetamide → 3-(5-Hydroxymethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(6-methoxy-1H-indol-3-yl)-pyrrolidine-2,5-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(6-Methoxy-1H-indol-3-yl)acetamide | HCID 17892596 | — |
| Reactant | (5-(tert-butyldimethylsilyloxymethyl)-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)oxo-acetic acid methyl ester | HCID 69743275 | — |
| Product | 3-(5-Hydroxymethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(6-methoxy-1H-indol-3-yl)-pyrrolidine-2,5-dione | HCID 22556870 | — |
Reaction Steps
Beginning with (5-(tert-butyldimethylsilyloxymethyl)-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl]oxoacetic acid methyl ester and (6-methoxy-1H-indol-3-yl)acetamide, the title compound was prepared essentially as described in Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06867198B2 |
| Source dataset | uspto-grants-2005_03 |
| ORD ID | ord-790c4c0c2fb44ddca5b15357761e60df |
| Source note | uspto-grants-2005_03 |