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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 984000Generated: November 2, 2026

2-(6-fluoro-1H-indol-3-yl)acetamide → 3-(5-(methoxy)methyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(6-fluoro-1H-indol-3-yl)pyrrole-2,5-dione

https://huagongshe.com/reaction/984000

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(6-fluoro-1H-indol-3-yl)acetamideHCID 21950062—
Reactant(5-methoxymethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)oxoacetic acid methyl esterHCID 69743508—
Product3-(5-(methoxy)methyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(6-fluoro-1H-indol-3-yl)pyrrole-2,5-dioneHCID 22556733—

Reaction Steps

Beginning with (5-methoxymethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)oxoacetic acid methyl ester and (6-fluoro-1H-indol-3-yl)acetamide, the title compound was prepared essentially as described in Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06867198B2
Source datasetuspto-grants-2005_03
ORD IDord-3deba3b1366f40ad8ee2ac38c32aba33
Source noteuspto-grants-2005_03