HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-carboxycinnamate → 4-(3-Methoxy-3-oxopropyl)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-carboxycinnamate | HCID 54440358 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 4-(3-Methoxy-3-oxopropyl)benzoic acid | HCID 11310294 | — |
Reaction Steps
8 g (38.8 mmol) of 4-(2-methoxycarbonylvinyl)benzoic acid (step a) were suspended in 250 ml of dioxane and hydrogenated under 1 bar of hydrogen over palladium/charcoal (10%) at room temperature for 7 h. The mixture was filtered and the solvent was evaporated in vacuo. Yield: 8.05 g (100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06867213B2 |
| Source dataset | uspto-grants-2005_03 |
| ORD ID | ord-264e2e5f590047e28260ed0233351d01 |
| Source note | uspto-grants-2005_03 |