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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 984176Generated: October 30, 2026

Ethyl 2-chloroisonicotinate → Ethyl 2-(3,5-dimethoxy-4-isopropoxyphenyl)isonicotinate

https://huagongshe.com/reaction/984176

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-chloroisonicotinateHCID 2762942—
Reactant4-Isopropoxy-3,5-dimethoxyphenylboronic acidHCID 22485594—
ProductEthyl 2-(3,5-dimethoxy-4-isopropoxyphenyl)isonicotinateHCID 22557851—

Reaction Steps

To a solution of 3,5-dimethoxy-4-isopropoxyphenylboronic acid (1.23 g) and ethyl 2-chloroisonicotinate (0.95 g) were condensed in the same manner as described in Preparation Example 1 to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06867221B2
Source datasetuspto-grants-2005_03
ORD IDord-bf43d29b7734498b929a9f04435ab14a
Source noteuspto-grants-2005_03