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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 984179Generated: October 31, 2026

Benzylamine → 4-Benzylamino-1-[[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl]piperidine

https://huagongshe.com/reaction/984179

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzylamineHCID 7504—
Reactant[2-(3,4,5-Trimethoxyphenyl)pyridin-4-yl]methyl-4-piperidoneHCID 22557811—
Product4-Benzylamino-1-[[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl]piperidineHCID 12043484—

Reaction Steps

1-[[2-(3,4,5-Trimethoxyphenyl)pyridin-4-yl]methyl-4-piperidone (1.40 g) and benzylamine (0.51 g) was condensed in the same manner as described in Preparation Example 37 to give the title compound as yellow amorphous.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06867221B2
Source datasetuspto-grants-2005_03
ORD IDord-15a7b21872e144fd941a72a9b1d213d6
Source noteuspto-grants-2005_03