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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 984223Generated: November 3, 2026

4-Chloromethyl-2-(3,4,5-trimethoxyphenyl) pyridine → HCID 22557903, compound

https://huagongshe.com/reaction/984223

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloromethyl-2-(3,4,5-trimethoxyphenyl) pyridineHCID 12019237—
ReactantHCID 22557994HCID 22557994—
ProductHCID 22557903HCID 22557903—

Reaction Steps

4-Propargylamino-1-[[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl]piperidine (227 mg) and 4-chloromethyl-2-(3,4,5-trimethoxyphenyl)pyridine (226 mg) were condensed in the same manner as described in Example 9. The title compound was obtained as yellow powder after converting a free base to a tetrahydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06867221B2
Source datasetuspto-grants-2005_03
ORD IDord-2f7768c2eec64023b94a5fbe7d4b7f3a
Source noteuspto-grants-2005_03