HRID984238

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COc1ccc(NC2CCN(C(=O)OC(C)(C)C)CC2)cc1

HCID2776119

tert-Butyl 4-(4-methoxyanilino)piperidine-1-carboxylate

C17H26N2O3

HCID22558066

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(N(C(=O)c2cccc(-c3cc(OC)c(OC)c(OC)c3)c2)C2CCN(C(=O)OC(C)(C)C)CC2)cc1

HCID22557968

未命名化合物

PROCEDURE

实验过程

4-(p-Anisidino)-1-(tert-butoxycarbonyl)piperidine (613 mg) and 3-(3,4,5-trimethoxyphenyl)benzoic acid (577 mg) were condensed in the same manner as described in Example 1 to give the title compound.

WORKUP

后处理

customcondensed in the same manner

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-22e07a469af946be9539b26e62324c2d
来源数据集: uspto-grants-2005_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06867221B2
来源说明: uspto-grants-2005_03

反应 SMILES

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([NH:9][CH:10]2[CH2:15][CH2:14][N:13]([C:16]([O:18][C:19]([CH3:22])([CH3:21])[CH3:20])=[O:17])[CH2:12][CH2:11]2)=[CH:5][CH:4]=1.[CH3:23][O:24][C:25]1[CH:26]=[C:27]([C:35]2[CH:36]=[C:37]([CH:41]=[CH:42][CH:43]=2)[C:38](O)=[O:39])[CH:28]=[C:29]([O:33][CH3:34])[C:30]=1[O:31][CH3:32]>>[C:19]([O:18][C:16]([N:13]1[CH2:14][CH2:15][CH:10]([N:9]([C:6]2[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:8][CH:7]=2)[C:38](=[O:39])[C:37]2[CH:41]=[CH:42][CH:43]=[C:35]([C:27]3[CH:26]=[C:25]([O:24][CH3:23])[C:30]([O:31][CH3:32])=[C:29]([O:33][CH3:34])[CH:28]=3)[CH:36]=2)[CH2:11][CH2:12]1)=[O:17])([CH3:22])([CH3:21])[CH3:20]