HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloromethyl-2-(3,4,5-trimethoxyphenyl) pyridine → 1-(tert-butoxycarbonyl)-4-[N-(4-butoxyphenyl)-N-[[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl]amino]piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloromethyl-2-(3,4,5-trimethoxyphenyl) pyridine | HCID 12019237 | — |
| Reactant | 1-(Tert-butoxycarbonyl)-4-(4-butoxyphenylamino)piperidine | HCID 22557944 | — |
| Product | 1-(tert-butoxycarbonyl)-4-[N-(4-butoxyphenyl)-N-[[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl]amino]piperidine | HCID 22557914 | — |
Reaction Steps
1-(tert-Butoxycarbonyl)-4-[(4-butoxyphenyl)amino]piperidine (696 mg) and 4-chloromethyl-2-(3,4,5-trimethoxyphenyl)pyridine (588 mg) was treated in the same manner as described in Example 9 to give light yellow amorphous of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06867221B2 |
| Source dataset | uspto-grants-2005_03 |
| ORD ID | ord-3b52c30f3e1f4b318f19d9e815f59c97 |
| Source note | uspto-grants-2005_03 |