HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Trifluoromethoxy)aniline → 1-(Tert-butoxycarbonyl)-4-[[4-(trifluoromethoxy)phenyl]amino]piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Trifluoromethoxy)aniline | HCID 600848 | — |
| Reactant | tert-Butyl 4-oxopiperidine-1-carboxylate | HCID 735900 | — |
| Product | 1-(Tert-butoxycarbonyl)-4-[[4-(trifluoromethoxy)phenyl]amino]piperidine | HCID 6623709 | — |
Reaction Steps
1-(tert-Butoxycarbonyl)-4-piperidone (5.00 g) and 4-(trifluoromethoxy)aniline (4.23 g) was treated in the same manner as described in Preparation Example 37 to give white powder of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06867221B2 |
| Source dataset | uspto-grants-2005_03 |
| ORD ID | ord-92fa68d460a645a490eab0ce62bf4322 |
| Source note | uspto-grants-2005_03 |