HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloromethyl-5-(3,4,5-trimethoxyphenyl)pyridine → 1-(tert-butoxycarbonyl)-4-[N-[4-(methylthio)phenyl]-N-[[3-(3,4,5-trimethoxyphenyl) pyridin-5-yl]methyl]amino]piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloromethyl-5-(3,4,5-trimethoxyphenyl)pyridine | HCID 22557874 | — |
| Reactant | 1-(Tert-butoxycarbonyl)-4-[[4-(methylthio)phenyl]amino]piperidine | HCID 22558035 | — |
| Product | 1-(tert-butoxycarbonyl)-4-[N-[4-(methylthio)phenyl]-N-[[3-(3,4,5-trimethoxyphenyl) pyridin-5-yl]methyl]amino]piperidine | HCID 22557843 | — |
Reaction Steps
1-(tert-Butoxycarbonyl)-4-[[4-(methylthio)phenyl]amino]piperidine (645 mg) and 5-chloromethyl-3-(3,4,5-trimethoxyphenyl)pyridine (588 mg) was treated in the same manner as described in Example 9 to give light yellow amorphous of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06867221B2 |
| Source dataset | uspto-grants-2005_03 |
| ORD ID | ord-99c9be5a64c841f6862b5514a4949544 |
| Source note | uspto-grants-2005_03 |