HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 4-((4-bromophenyl)amino)piperidine-1-carboxylate → 4-[N-(4-bromophenyl)-N-[[3-(3,4,5-trimethoxyphenyl)pyridin-5-yl]methyl]amino]-1-(tert-butoxycarbonyl)piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 4-((4-bromophenyl)amino)piperidine-1-carboxylate | HCID 11210451 | — |
| Reactant | 3-Chloromethyl-5-(3,4,5-trimethoxyphenyl)pyridine | HCID 22557874 | — |
| Product | 4-[N-(4-bromophenyl)-N-[[3-(3,4,5-trimethoxyphenyl)pyridin-5-yl]methyl]amino]-1-(tert-butoxycarbonyl)piperidine | HCID 22557853 | — |
Reaction Steps
4-(4-Bromophenyl)amino-1-(tert-butoxycarbonyl)piperidine (711 mg) and 5-chloromethyl-3-(3,4,5-trimethoxyphenyl)pyridine (588 mg) was treated in the same manner as described in Example 9 to give light yellow amorphous of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06867221B2 |
| Source dataset | uspto-grants-2005_03 |
| ORD ID | ord-43a2fcbe3cff4a0eb0aaf85e3f90c7bb |
| Source note | uspto-grants-2005_03 |