HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Difluoroaniline → 1-Boc-4-[(3,4-difluorophenyl)amino]-piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Difluoroaniline | HCID 77469 | — |
| Reactant | tert-Butyl 4-oxopiperidine-1-carboxylate | HCID 735900 | — |
| Product | 1-Boc-4-[(3,4-difluorophenyl)amino]-piperidine | HCID 22558033 | — |
Reaction Steps
1-(tert-Butoxycarbonyl)-4-piperidone (5.00 g) and 3,4-difluoroaniline (3.09 g) was treated in the same manner as described in Preparation Example 37 to give light brown prism crystal of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06867221B2 |
| Source dataset | uspto-grants-2005_03 |
| ORD ID | ord-b6ca679ff84e45fe9b0b66d52c225eee |
| Source note | uspto-grants-2005_03 |