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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 984293Generated: October 29, 2026

1-Boc-4-AP → 1-(tert-butoxycarbonyl)-4-[N-phenyl-N-[[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl]amino]piperidine

https://huagongshe.com/reaction/984293

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Boc-4-APHCID 1491502—
Reactant4-Chloromethyl-2-(3,4,5-trimethoxyphenyl) pyridineHCID 12019237—
Product1-(tert-butoxycarbonyl)-4-[N-phenyl-N-[[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl]amino]piperidineHCID 22557812—

Reaction Steps

1-(tert-Butoxycarbonyl)-4-phenylaminopiperidine (553 mg) and 4-chloromethyl-2-(3,4,5-trimethoxyphenyl)pyridine (588 mg) was treated in the same manner as described in Example 9 to give light yellow amorphous of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06867221B2
Source datasetuspto-grants-2005_03
ORD IDord-f849c146fba84b9a86b7d9fa0e3c9783
Source noteuspto-grants-2005_03