Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 984343Generated: November 4, 2026

Ethyl (2S)-2-ethoxy-3-(4-hydroxyphenyl)propanoate → (E)-(S)-Ethyl 3-{4-[3-(3'-Acetyl-biphenyl-4-yl)-but-2-enyloxy]-phenyl}-2-ethoxy-propionate

https://huagongshe.com/reaction/984343

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl (2S)-2-ethoxy-3-(4-hydroxyphenyl)propanoateHCID 9816147—
Reactant(E)-3-(3'-acetyl-biphenyl-4-yl)-but-2-en-1-olHCID 69799799—
Product(E)-(S)-Ethyl 3-{4-[3-(3'-Acetyl-biphenyl-4-yl)-but-2-enyloxy]-phenyl}-2-ethoxy-propionateHCID 8658995365.8%

Reaction Steps

The title compound (0.16 g, 65% yield) was prepared from (E)-3-(3′-acetyl-biphenyl-4-yl)-but-2-en-1-ol (0.133 g, 0.50 mmol) and (S)-ethyl 2-ethoxy-3-(4-hydroxyphenyl)-propionate (0.125 g, 0.525 mmol) by a procedure analogous to that described in example 52 c.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06867218B2
Source datasetuspto-grants-2005_03
ORD IDord-63c624cf34a749369a0315e2baaf8b5a
Source noteuspto-grants-2005_03