Ethyl trans-4-Bromocinnamate → HCID 69796659, compound

HRID 984348Notes

Reaction equation

HRID 984348 reaction equation
[CH2:1]([O:3][C:4](=[O:14])/[CH:5]=[CH:6]/[C:7]1[CH:12]=[CH:11][C:10](Br)=[CH:9][CH:8]=1)[CH3:2].[Cl:15][C:16]1[C:21]([Cl:22])=[CH:20][CH:19]=[CH:18][C:17]=1B(O)O>>[CH2:1]([O:3][C:4](=[O:14])[C@@H:5]([O:3][CH2:1][CH3:2])[CH2:6][C:7]1[CH:12]=[CH:11][C:10]([O:14][CH2:4]/[CH:5]=[CH:6]/[C:7]2[CH:12]=[CH:11][C:10]([C:17]3[CH:18]=[CH:19][CH:20]=[C:21]([Cl:22])[C:16]=3[Cl:15])=[CH:9][CH:8]=2)=[CH:9][CH:8]=1)[CH3:2]

Participants

3

Reactant 2

HCID 688115Ethyl trans-4-BromocinnamateHCID 27346612,3-Dichlorobenzeneboronic acid

Product 1

HCID 69796659HCID 69796659, compound

Procedure

The title compound was prepared from (E)-3-(4-bromo-phenyl)-acrylic acid ethyl ester and 2,3-dichlorobenzene boronic acid by a sequence analogous to that described in example 52a-c.

Sources & evidence

ORD record
ord-a38fd92590da427b9a991d271e3df41e
Source dataset
uspto-grants-2005_03
Patent number
US06867218B2

Reaction notes

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