HCID 22557642, compound → HCID 22557656, compound

HRID 984350Notes

Reaction equation

HRID 984350 reaction equation
[CH2:1]([C:9]1[CH:10]=[C:11]([CH2:23][OH:24])[CH:12]=[C:13]([CH2:15][CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH:14]=1)[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[Cr](Cl)([O-])(=O)=O.[NH+]1C=CC=CC=1>ClCCl>[CH2:1]([C:9]1[CH:10]=[C:11]([CH:12]=[C:13]([CH2:15][CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH:14]=1)[CH:23]=[O:24])[CH2:2][C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1

Participants

4

Reactant 2

HCID 22557642HCID 22557642, compoundHCID 178418287HCID 178418287, compound

Product 1

HCID 22557656HCID 22557656, compoundYield 64.6%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a solution of (3,5-diphenethyl-phenyl)-methanol (2.0 g, 6.4 mmol) in dry dichloromethane (30 mL) was added pyridinium chlorochromate (1.4 g, 6.4 mmol) and the mixture was stirred at room temperature for 16 h. The product was purified by flash chromatography using dichloromethane as solvent to give 1.3 g 3,5-diphenethyl-benzaldehyde.

Workup

  1. customThe product was purified by flash chromatography

Sources & evidence

ORD record
ord-469f865d4bbe49a4b2852e0889ca4892
Source dataset
uspto-grants-2005_03
Patent number
US06867218B2

Reaction notes

Loading…