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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 984354Generated: October 29, 2026

Ethyl (2S)-2-ethoxy-3-(4-hydroxyphenyl)propanoate → (E)-(S)-Ethyl 2-Ethoxy-3-{4-[3-(4-furan-2-yl-phenyl)-but-2-enyloxy]-phenyl}propionate

https://huagongshe.com/reaction/984354

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl (2S)-2-ethoxy-3-(4-hydroxyphenyl)propanoateHCID 9816147—
Reactant(E)-3-(4-furan-2-yl-phenyl)-but-2-en-1-olHCID 69800884—
Product(E)-(S)-Ethyl 2-Ethoxy-3-{4-[3-(4-furan-2-yl-phenyl)-but-2-enyloxy]-phenyl}propionateHCID 8675894478%

Reaction Steps

The title compound (678 mg, 77%) was prepared from (E)-3-(4-furan-2-yl-phenyl)-but-2-en-1-ol (430 mg, 2.0 mmol) and (S)-ethyl 2-ethoxy-3-(4-hydroxyphenyl)-propionate (526 mg, 2.21 mmol) by a procedure analogous to that described in example 52c.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06867218B2
Source datasetuspto-grants-2005_03
ORD IDord-53224cbd90bf41f8bc2c437e73561ca0
Source noteuspto-grants-2005_03