HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl (2S)-2-ethoxy-3-(4-hydroxyphenyl)propanoate → (E)-(S)-Ethyl 3-{4-[3-(2',5'-Dimethoxy-biphenyl-4-yl)-but-2-enyloxy]-phenyl}-2-ethoxy-propionate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl (2S)-2-ethoxy-3-(4-hydroxyphenyl)propanoate | HCID 9816147 | — |
| Reactant | (E)-3-(2',5'-dimethoxy-biphenyl-4-yl)-but-2-en-1-ol | HCID 69796389 | — |
| Product | (E)-(S)-Ethyl 3-{4-[3-(2',5'-Dimethoxy-biphenyl-4-yl)-but-2-enyloxy]-phenyl}-2-ethoxy-propionate | HCID 86758945 | 61% |
Reaction Steps
The title compound (0.765 g, 61%) was prepared as a colourless gum from (E)-3-(2′,5′-dimethoxy-biphenyl-4-yl)-but-2-en-1-ol (0.711 g, 2.50 mmol) and (S)-ethyl 2-ethoxy-3-(4-hydroxyphenyl)-propionate (0.655 g, 2.75 mmol) by a procedure analogous to that described in example 52c.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06867218B2 |
| Source dataset | uspto-grants-2005_03 |
| ORD ID | ord-1eec3a9df17a4f4bada29e5411a5257a |
| Source note | uspto-grants-2005_03 |