4-Isopropylphenylboronic acid → HCID 22557676, compound

HRID 984373Notes

Reaction equation

HRID 984373 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5](/[C:8](/[CH3:15])=[CH:9]/[C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:4][CH:3]=1.[CH:16]([C:19]1[CH:24]=[CH:23][C:22](B(O)O)=[CH:21][CH:20]=1)([CH3:18])[CH3:17]>>[CH:16]([C:19]1[CH:24]=[CH:23][C:22]([C:2]2[CH:7]=[CH:6][C:5](/[C:8](/[CH3:15])=[CH:9]/[C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:4][CH:3]=2)=[CH:21][CH:20]=1)([CH3:18])[CH3:17]

Participants

3

Reactant 2

HCID 27734804-Isopropylphenylboronic acidHCID 15933615(E)-ethyl 3-(4-bromophenyl)-but-2-enoate

Product 1

HCID 22557676HCID 22557676, compound

Procedure

The colourless solid, (E)-ethyl 3-(4′-isopropyl-biphenyl-4-yl)-but-2-enoate was prepared from (E)-ethyl 3-(4-bromophenyl)-but-2-enoate (example 50a) and 4-isopropylphenyl boronic acid by a procedure analogous to that described in example 52a.

Sources & evidence

ORD record
ord-c5dadd2931cf4f34bbcc203cc20eadf5
Source dataset
uspto-grants-2005_03
Patent number
US06867218B2

Reaction notes

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