Sodium Hydroxide → HCID 69796728, compound

Participants

Reaction Steps

The title compound was prepared from (E)-(S)-ethyl 2-ethoxy-3-{4-[3-(4′-isopropyl-biphenyl-4-yl)-but-2-enyloxy]-phenyl}-propionate (Example 103) (400 mg, 0.822 mmol) and sodium hydroxide (1M, 3.29 ml, 3.29 mmol) by a procedure analogous to that described in example 51, yielding (E)-(S)-2-ethoxy-3-{4-[3-(4′-isopropyl-biphenyl-4-yl)-but-2-enyloxy]-phenyl}-propionic acid (380 mg, 100%) as a beige coloured solid.

Provenance & Evidence