Sodium Hydroxide → HCID 69796282, compound

Participants

Reaction Steps

The title compound was prepared from (E)-(S)-ethyl 2-ethoxy-3-{4-[3-(3′-methoxy-biphenyl-4yl)-but-2-enyloxy]-phenyl}-propionate (example 113) (230 mg, 0.49 mmol) and sodium hydroxide (1M, 0.97 ml, 0.97 mmol) by a procedure analogous to that described in example 51, yielding (E)-(S)-2-ethoxy-3-{4-[3-(3′-methoxy-biphenyl-4-yl)-but-2-enyloxy]-phenyl}-propionic acid (183 mg, 85%) as a colourless solid.

Provenance & Evidence