反应详情

The title compound was prepared from (E)-(S)-ethyl 3-{4-[3-(3′,5′-di-tert-butyl-biphenyl-4-yl)-allyloxy]-phenyl}-2-ethoxy-propionate (example 129) (110 mg, 0.20 mmol) and sodium hydroxide (1M, 0.8 ml, 0.8 mmol) by a procedure analogous to that described in example 51, yielding ((E)-(S)-3-{4-[3-(3′,5′-di-tert-butyl-biphenyl-4-yl)-allyloxy]-phenyl}-2-ethoxy-propionic acid (92 mg, 88%) as a colourless solid.