HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chlorobenzaldehyde → HCID 9826426, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chlorobenzaldehyde | HCID 6996 | — |
| Reactant | 6-Amino-1-hexanol | HCID 19960 | — |
| Reactant | 2,4-Dichlorobenzenethiol | HCID 70730 | — |
| Reactant | 2-Bromobenzenethiol | HCID 80598 | — |
| Reactant | 3-Acetamidopyrrolidine | HCID 522715 | — |
| Reactant | 3-Chloro-4-fluorobenzaldehyde | HCID 593866 | — |
| Product | HCID 9826426 | HCID 9826426 | — |
Reaction Steps
The title compound was prepared by the procedures described in Example 1 substituting 2,4-dichlorothiophenol with 2-bromothiophenol, 2-chlorobenzaldehyde with 3-chloro-4-fluoro-benzaldehyde, and 6-amino-1-hexanol with 3-acetamidopyrrolidine. 1H NMR (DMSO-d6, 300 MHz) δ 8.14 (m, 1H), 8.07 (dd, J=9.8, 1.7 Hz, 1H), 7.80 (d, J=1.8 Hz, 1H), 7.64 (dd, J=8.1, 1.7 Hz, 1H), 7.25-7.47 (m, 4H), 7.10 (t, J=7.8 Hz, 1H), 7.03 (dd, J=8.1, 1.7 Hz, 1H), 3.45-4.34 (m, 6H), 2.02 (m, 2H), 1.81 (ap d, J=1.4 Hz, 1H). HRMS calculated for C21H20N2O2S1Br1C1: 479.0196. Observed: 479.0183.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06867203B2 |
| Source dataset | uspto-grants-2005_03 |
| ORD ID | ord-437493229f85482fbfc2ac9136be6721 |
| Source note | uspto-grants-2005_03 |