Sodium Chloride → HCID 73991839, compound

Participants

Reaction Steps

400 ml saturated potassium carbonate solution is added to 1.94 g (5.05 mmol) 3-acetoxy-11-(tert-butyl-dimethylsilyloxy)-6,10-dimethyl-5-undecene-2-one in 20.0 ml methanol. After termination of the reaction (accurate DC control, e.g. approx. 10 min at room temperature), 30 ml of the NaCl solution is added and five times extracted with 30 ml diethylether. The combined organic phases are washed again with NaCl solution, and dried over sodium sulfate, the solvent was then removed in the vacuum, and silica gel chromatography was performed with the residue.

Provenance & Evidence