3-Bromopyridine → HCID 13304847, compound

Participants

Reaction Steps

Using the general procedure, 3-bromopyridine (96 μL, 1.0 mmol) was coupled with 3-(aminomethyl)pyridine (153 μL, 1.5 mmol) at 90° C. for 20 h. Purification of the crude product by column chromatography on silica gel using dichloromethane(saturated with ammonia)/methanol (15:1) as eluent afforded the desired product as a light yellow liquid (153 mg, 83% yield). Rf=0.4 (dichloromethane(saturated with ammonia)/methanol=10:1).

Provenance & Evidence