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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 984840Generated: October 30, 2026

8-Chlorotheophylline → Purine-2,6(1H,3H)-dione, 7-(2-bromobenzyl)-8-chloro-1,3-dimethyl-

https://huagongshe.com/reaction/984840

Reaction equation

Participants

RoleNameHCIDCharge
Reactant8-ChlorotheophyllineHCID 10661—
Reactant2-Bromobenzyl bromideHCID 76965—
ProductPurine-2,6(1H,3H)-dione, 7-(2-bromobenzyl)-8-chloro-1,3-dimethyl-HCID 598207—

Reaction Steps

8-Chlorotheophylline and 2-bromobenzyl bromide were reacted and purified as described in the General procedure CC, step A, to afford 83A as white crystals in 57%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06869947B2
Source datasetuspto-grants-2005_03
ORD IDord-48f2e585b85846c99c1dc120a7ff4dd1
Source noteuspto-grants-2005_03