o-Xylyl bromide → HCID 759632, compound

HRID 984841Notes

Reaction equation

[Cl:1][C:2]1[NH:11][C:10]2[C:9](=[O:12])[N:7]([CH3:8])[C:6](=[O:13])[N:5]([CH3:14])[C:4]=2[N:3]=1.[CH3:15][C:16]1[CH:23]=[CH:22][CH:21]=[CH:20][C:17]=1[CH2:18]Br>>[Cl:1][C:2]1[N:11]([CH2:15][C:16]2[CH:23]=[CH:22][CH:21]=[CH:20][C:17]=2[CH3:18])[C:10]2[C:9](=[O:12])[N:7]([CH3:8])[C:6](=[O:13])[N:5]([CH3:14])[C:4]=2[N:3]=1

Participants

Reactant 2

HCID 6992o-Xylyl bromide

HCID 106618-Chlorotheophylline

Product 1

HCID 759632HCID 759632, compound

Procedure

8-Chlorotheophylline and 2-methylbenzyl bromide were reacted and purified as described in the General procedure C, step A, to afford 85A as white crystals in 86%.

Workup

custompurified

Sources & evidence

ORD record: ord-38d90ceb76eb464d8c0e69c1dd8922e8
Source dataset: uspto-grants-2005_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06869947B2

Reaction notes

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