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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 984985Generated: October 30, 2026

1-Benzylpiperazine → 4-(4-benzyl-1-piperazinyl)methyl-2-isobutyl-6-(4-methylphenyl)-2H-pyridazin-3-one

https://huagongshe.com/reaction/984985

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-BenzylpiperazineHCID 75994—
Reactant2-isobutyl-4-methanesulfonyloxymethyl-6-(4-methylphenyl)-2H-pyridazin-3-oneHCID 21991589—
Product4-(4-benzyl-1-piperazinyl)methyl-2-isobutyl-6-(4-methylphenyl)-2H-pyridazin-3-oneHCID 2199148797.7%

Reaction Steps

Following the procedure of Example 1(10), 2-isobutyl-4-methanesulfonyloxymethyl-6-(4-methylphenyl)-2H-pyridazin-3-one and 1-benzylpiperazine were reacted to yield the title compound as a pale yellow oil (yield: 97.7%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06869954B2
Source datasetuspto-grants-2005_03
ORD IDord-1eb59927460043038cdb32982222ab06
Source noteuspto-grants-2005_03