HCID 10138875, compound → HCID 22555956, compound

Participants

Reaction Steps

A solution of 115 (1.71 g, 3.79 mmol) in ethyl acetate (200 mL) was cooled in an ice bath with stirring. Hydrogen chloride gas was bubbled through the solution for 15 min. then the contents of the reaction flask were warmed to room temperature. After 1.25 h the solvent was removed in vacuo and the remaining residue was triturated with ether to give 116 as a white solid (1.37 g, 3.54 mmol, 93.6%).

Provenance & Evidence