HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boron tribromide → 6-Hydroxy-2-methyl-1H-indol-3-carboxylic acid methylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boron tribromide | HCID 25134 | — |
| Reactant | 6-Methoxy-2-methyl-1H-indol-3-carboxylic acid methylamide | HCID 20767871 | — |
| Product | 6-Hydroxy-2-methyl-1H-indol-3-carboxylic acid methylamide | HCID 20767862 | — |
Reaction Steps
This material was prepared from 6-methoxy-2-methyl-1H-indol-3-carboxylic acid methylamide 24a by treatment with BBr3 in a manner as previously described for example 1d. 1H NMR (300 MHz, CD3OD) δ7.52 (1H, d, J=8.7 Hz), 6.72 (1H, d, J=2.3 Hz), 6.65 (1H, dd, J=2.3, 8.7 Hz), 2.93 (3H, s), 2.55 (3H, s). LCMS (ESI+) [M+H]/z Calc'd 205, found 205.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06869962B2 |
| Source dataset | uspto-grants-2005_03 |
| ORD ID | ord-bc032f39e70a42ce94f86d5db9f14bae |
| Source note | uspto-grants-2005_03 |