Cesium carbonate → HCID 69368700, compound

Participants

Role	Name	HCID	Charge
Reactant	Cesium carbonate	HCID 10796	—
Reactant	6-hydroxy-N,1,2-trimethyl-1H-indole-3-carboxamide	HCID 22143530	—
Reactant	2-(Azetidin-1-ylcarbonyl)-7-chlorothieno[3,2-b]pyridine	HCID 22143549	—
Product	HCID 69368700	HCID 69368700	—

Reaction Steps

This material was prepared by the reaction of 2-(azetidin-1-ylcarbonyl)-7-chlorothieno[3,2-b]pyridine 25a with 6-hydroxy-1,2-dimethyl-1H-indole-3-carbyxylic acid methylamide 16e and Cs2CO3 in a manner as previously described for example 1. 1H NMR (300 MHz, CD3OD) δ8.41 (1H, d, J=5.5 Hz), 7.80 (1H, d, J=3.20 Hz), 7.74 (1H, d, J=11.68 Hz), 7.30 (1H, s), 6.94 (1H, d, J=8.66 Hz), 6.62 (1H, d, J=5.5 Hz), 4.64-4.59 (2H, m), 4.20-4.15 (2H, m), 3.63 (3H, s), 2.85 (3H, s), 2.57 (3H, s), 2.44-2.36 (2H, m). LCMS (ESI+) [M+H]/z Calc'd 435, found 435.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06869962B2
Source dataset	uspto-grants-2005_03
ORD ID	ord-152443a1379f4e9196c389ef60d477aa
Source note	uspto-grants-2005_03