Triethylamine → HCID 20767772, compound

Participants

Reaction Steps

This material was prepared from lithium 7-chlorothieno[3,2-b]pyridine-2-carboxylic acid (2.69 g, 12.25 mmole), SOCl2 (10 ml), L-serine methyl ester hydrochloride (2.86 g, 18.4 mmole) and Et3N (5.12 ml, 37.7 mmole) in a manner as previously described for example 9d to give a white solid (2.09 g, 54%). 1H NMR (300 MHz, CDCl3) δ8.61 (1H, d, J=5.1 Hz), 8.02 (1H, s), 7.35 (1H, d, J=5.1 Hz), 4.89 (1H, m), 4.15 (2H, m), 3.84 (3H, m).

Provenance & Evidence