HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boron tribromide → 2-Methylbenzofuran-6-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boron tribromide | HCID 25134 | — |
| Reactant | 6-Methoxy-2-methylbenzofuran | HCID 13013073 | — |
| Reactant | 6-Hydroxy-n,2-dimethyl-1-benzothiophene-3-carboxamide | HCID 20767863 | — |
| Product | 2-Methylbenzofuran-6-ol | HCID 12203498 | 75.5% |
Reaction Steps
This material was prepared from 6-methoxy-2-methylbenzofuran (1.00 g, 6.17 mmole) by treatment with BBr3 in a manner as previously described for 1d to give a colorless oil (690 mg, 75%) which solidified on standing. 1H NMR (DMSO-d6) δ9.32 (1H, s), 7.23 (1H, d, J=8.3 Hz), 6.80 (1H, s), 6.64 (1H, d, J=8.3 Hz), 6.37 (1H, s), 2.35 (3H, s).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06869962B2 |
| Source dataset | uspto-grants-2005_03 |
| ORD ID | ord-2b3273bbd7e34993a54335a599cf626e |
| Source note | uspto-grants-2005_03 |