HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cesium carbonate → Methyl 2-Methyl-6-[thieno[3,2-b]pyridin-7-yloxy]benzofuran-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 7-Chlorothieno[3,2-b]pyridine | HCID 11275251 | — |
| Reactant | Methyl 6-hydroxy-2-methylbenzofuran-3-carboxylate | HCID 22143518 | — |
| Product | Methyl 2-Methyl-6-[thieno[3,2-b]pyridin-7-yloxy]benzofuran-3-carboxylate | HCID 22143628 | — |
Reaction Steps
This material was prepared by the reaction of 7-chloro-thieno[3,2-b]pyridine with methyl 6-hydroxy-2-methylbenzofuran-3-carboxylate 89c and Cs2CO3 in a manner as previously described. 1H NMR (CDCl3) δ8.48 (1H, d, J=5.3 Hz), 7.99 (1H, d, J=8.3 Hz), 7.74 (1H, d, J=5.6 Hz), 7.56 (1H, d, J=5.3 Hz), 7.29 (1H, d, J=2.0 Hz), 7.16 (1H, dd, J=8.6, 2.3 Hz), 6.53 (1H, d, J=5.3 Hz), 3.96 (3H, s), 2.79 (3H, s).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06869962B2 |
| Source dataset | uspto-grants-2005_03 |
| ORD ID | ord-a3516724082e4302ae779db9cbe56e02 |
| Source note | uspto-grants-2005_03 |