2-Amino-5-phenyl-1,3,4-thiadiazole → 2-Methyl-6-(thieno[3,2-b]pyridin-7-yloxy)-benzofuran-3-carboxylic acid (5-phenyl-[1,3,4]thiadiazol-2-yl)-amide

Participants

Reaction Steps

This material was prepared from 2-methyl-6-[thieno[3,2-b]pyridin-7-yloxy]benzofuran-3-carboxylic acid 100 and 5-phenyl-[1,3,4]thiadiazol-2-ylamine in a similar manner as that described for example 102. 1H NMR (CD3CN/CD3OD) δ8.45 (1H, d, J=5.6 Hz), 8.00-7.95 (4H, m), 7.52-7.50 (4H, m), 7.48 (1H, d, J=2.3 Hz), 7.25 (1H, dd, J=8.6, 2.3 Hz), 6.66 (1H, d, J=5.3 Hz), 2.76 (3H, s).

Provenance & Evidence