3-[3-(Tri-n-butylstannanyl)phenyl]pyridine → 7-Methoxy-3-[3-(pyridin-3-yl)phenyl]imidazo[1,2-alpha]pyridine

Participants

Reaction Steps

The title compound was prepared in a similar manner to that described in Example 11 from 3-bromo-7-methoxyimidazo[1,2-α]pyridine and 3-[3-(tri-n-butylstannanyl)phenyl]pyridine to furnish a white crystalline solid, m.p. 153-154° C. 1H NMR (360 MHz, CDCl3) δH 3.89 (3H, s), 6.57 (1H, dd, J 2 and 8), 6.94 (1H, d, J 2), 7.37-7.43 (1H, m), 7.55-763 (4H, m), 7.72 (1H, s), 7.89-7.94 (1H, m), 8.19 (1H, d, J 7), 8.62-8.65 (1H, m), 8.90 (1H, s); m/z (ES+) 302 (M++H).

Provenance & Evidence