HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N-Dimethylsuccinamic acid → HCID 22507704, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N-Dimethylsuccinamic acid | HCID 75717 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 9886157 | — |
| Reactant | (+)-7-[1,4)Dioxan-2-yl-4-methoxy-benzothiazol-2-ylamine | HCID 22507697 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 22507704 | HCID 22507704 | — |
Reaction Steps
From N,N-dimethylsuccinamic acid, HATU and N-ethyldiisopropylamine in THF, then treatment with (+)-7-[1,4]dioxan-2-yl-4-methoxy-benzothiazol-2-ylamine. [α]D20=+21.9° (c=1.04, CHCl3), ES-MS m/e (%): 394 (M+H+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06872833B2 |
| Source dataset | uspto-grants-2005_03 |
| ORD ID | ord-a1e517830a254ecfa0d43c2c7046460c |
| Source note | uspto-grants-2005_03 |