HuagongsheHuagongshe Chemistry Print Report · For research reference only
Butyl Chloride → HCID 54462614, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Butyl Chloride | HCID 8005 | — |
| Reactant | 4-Methyl-5,6-dihydrofuro[2,3-d]pyrimidin-2-amine | HCID 4098832 | — |
| Reactant | 2-[(1,2-Dichloroethenyl)oxy]benzene-1-sulfonyl isocyanate | HCID 53930076 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 54462614 | HCID 54462614 | — |
Reaction Steps
To 300 mg of 2-amino-5,6-dihydro-4-methylfuro[2,3-d]pyrimidine in 25 ml of methylene chloride was added 20 ml of 2-(1,2-dichloroethen-1-yloxy)benzenesulfonyl isocyanate in methylene chloride from the previous example. After heating to reflux, the mixture was stirred overnight at room temfperature. Removal of the solvent in vacuo yielded an amber oil. Trituration of this oil with 1-chlorobutane gave a tan solid. After filtration and washing with ethyl ether, a yield of 0.8 g of a tan solid melting at 208°-210° was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | USH0000386 |
| Source dataset | uspto-grants-1987_12 |
| ORD ID | ord-79325ba1fc4a4e25b5859cfd8107f16a |
| Source note | uspto-grants-1987_12 |