Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Isopropanol | HCID 3776 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | Benzenepropanal, alpha,alpha,3-trimethyl- | HCID 13797308 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | Majantol | HCID 175948 | — |
Reaction Steps
44 g of 2,2-dimethyl-3-(3-methylphenyl)-propionaldehyde (according to Example 3) were added in small portions under argon and at 20° C. to a pre-mix of 150 ml of isopropanol and 3.8 g of sodium borohydride. The entire mixture was stirred for 24 hours at 20° C. Excess sodium borohydride was then decomposed by the dropwise addition of 2N HCl. The reaction mixture was then taken up in 150 ml of diethyl ether and extracted with water, 2N NaOH and, again, with water.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04710316 |
|---|
| Source dataset | uspto-grants-1987_12 |
|---|
| ORD ID | ord-c3daf21f1f544a39a01ecd90a322c1bf |
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| Source note | uspto-grants-1987_12 |
|---|
