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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 985936Generated: October 30, 2026

Butyl 4-chloro-3-oxobutanoate → n-butyl-4-chloro-3(R)-hydroxybutyrate

https://huagongshe.com/reaction/985936

Reaction equation

Participants

RoleNameHCIDCharge
ReactantButyl 4-chloro-3-oxobutanoateHCID 13705501—
SolventChloroformHCID 6212—
Productn-butyl-4-chloro-3(R)-hydroxybutyrateHCID 13705502—

Reaction Steps

The procedure of example 375 was repeated using n-butyl-4-chloroacetoacetate as the substrate to afford n-butyl-4-chloro-3(R)-hydroxybutyrate, [α]D23 +20.1° (c, 3.1, CHCl3).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04710468
Source datasetuspto-grants-1987_12
ORD IDord-032e47bb72134d45a10437668edd89a0
Source noteuspto-grants-1987_12