Benzyloxyamine hydrochloride → HCID 53908867, compound

HRID 986031Notes

Reaction equation

HRID 986031 reaction equation
[CH3:1][N:2]1[CH2:7][CH2:6][CH:5]=[C:4]([C:8](=O)[CH2:9][CH3:10])[CH2:3]1.Cl.[C:13]1([CH2:19][O:20][NH2:21])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[C:13]1([CH2:19][O:20][N:21]=[C:8]([C:4]2[CH2:3][N:2]([CH3:1])[CH2:7][CH2:6][CH:5]=2)[CH2:9][CH3:10])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 102312Benzyloxyamine hydrochlorideHCID 10176226HCID 10176226, compound

Product 1

HCID 53908867HCID 53908867, compoundYield 82%

Procedure

Examploying the general method of Example 5 above, but starting with 1-(1,2,5,6-tetrahydro-1-methyl-3-pyridinyl)-1-propanone and O-(phenylmethyl)hydroxylamine hydrochloride, the title compound was prepared in 82% yield and isolated as the ethanedioate salt, mp 137°-139° C.

Sources & evidence

ORD record
ord-e71838cb701b4c8fa5b4afff7d0098af
Source dataset
uspto-grants-1987_12
Patent number
US04710508

Reaction notes

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